Jan 21, 2020 · 4. Nickel Allergy. Metals, such as gold, silver, nickel, titanium, chromium and copper, are ubiquitous in our environment and are widely used in costume jewelry, coins, mobile phone and orthodontic materials [28,60,61,62].The orthodontic patients are exposed to a considerable amount of nickel, cobalt, titanium and other metals deriving from alloys.
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